BioSpace is proud to present its NextGen Bio “Class of 2023,” a list of the hottest recently launched life sciences companies in North America. To come up with this list, BioSpace evaluated companies that launched between September 2021 and September 2022 with Series A funding. They were then assessed using several different criteria and ranked […]
A snapshot of gene therapy and CAR T innovation, the emergence of protein stabilization, and new thinking in neurology
Study Rationale: Parkinson’s disease (PD) is associated with activating mutations in a protein kinase called LRRK2. In previous studies, we found that regulating LRRK2’s chemical modification by phosphorylation controls the inappropriate activation of the protein. Because LRRK2 phosphorylation is decreased in PD, we propose that enhancing LRRK2 phosphorylation at key sites on the protein will
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